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DMCA report, please send email to ΑDC. Jump to navigation Jump to search “AD4” redirects here. For the year, see AD 4. PBB GE PSEN2 211373 s at fs. PBB GE PSEN2 204262 s at fs.
Presenilin-2 is a protein that in humans is encoded by the PSEN2 gene. In melanocytic cells PSEN2 gene expression may be regulated by MITF. Candidate gene for the chromosome 1 familial Alzheimer’s disease locus”. Novel MITF targets identified using a two-step DNA microarray strategy”.
A potential role in modulating the threshold of cell death”. The presenilin 2 loop domain interacts with the mu-calpain C-terminal region”. A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer’s disease presenilin 2 protein”. Calsenilin: a calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment”. Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer’s disease-associated C-terminal fragment of presenilin 2″. Alzheimer’s disease-associated presenilin 2 interacts with DRAL, an LIM-domain protein”. Interaction of presenilins with the filamin family of actin-binding proteins”.
KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4″. Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch”. 1 signal transduction and betaAPP processing”. Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation”. Localization and possible functions of presenilins in brain”. Biology of presenilins as causative molecules for Alzheimer disease”. Recent insights on the pro-apoptotic phenotype elicited by presenilin 2 and its caspase and presenilinase-derived fragments”.
Talking Point on the role of presenilin mutations in Alzheimer disease”. Loss-of-function presenilin mutations in Alzheimer disease. This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it. VMR 75 RAPID BLOW RAMMERSTwo popular sizes to match most applications. THE BEST OF BOTH WORLDS JUST GOT BETTER.
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